Phosphofructokinase is a four-subunit protein with four active sites. phosphofructokinase catalyzes step 3 of glycolysis, converting fructose-6-phosphate to fructose-1,6-bisphosphate. phosphoenolpyruvate (pep) is the product of step 9 of glycolysis. the pep concentration in the cell affects phosphofructokinase activity. select the true statements about pep regulation of phosphofructokinase.
PEP is included in the regulation of phosphofructokinase (PFK). PFK is allosterically inhibited by PEP which means that PEP binds to PFK which results in a conformational change of PFK. As a result of this PFK is inhibited. High levels of PEP indicate a sufficient cellular energy supply and therefore there is no need for further glycolysis.